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6,713 words — headwords with part of speech, pronunciation, and a plain-language definition.

destruir: to destroy
destupidor: plunger
destupir: to clear
desturcar: to break, destroy; to be or go insane (i.e. "desturcado mental")
desubicación: disorientation
desubicado: unseemly
desubicar: to disorientate; to become disorientated
desuerado: the process of removing whey to make cheese
desuerar: to remove the whey from
desuetud: disuse; desuetude
desulfuración: desulfurization
desulfurización: desulphurization
desulfurizador: desulfurizing
desungulación: dysungulation
desunir: to disjoin, disconnect, to divide
desunión: breakage, breakup, separation; disunity
desusadamente: obsoletely
desusado: disused; dated, obsolete
desusar: to stop using; to fall into disuse
desuscribir: to unsubscribe; to unsubscribe, deregister; to cancel
desuscripción: unsubscribing
desuso: disuse (lack of use); obsolescence, desuetude (state of being no more used); abeyance; stay
desvaciar: synonym of vaciar
desvainar: to shell (remove the covering of a vegetable)
desvalido: helpless
desvalijamiento: robbery
desvalijar: to rob, clean out (rob everything someone has)
desvalimiento: helplessness
desvalor: cowardice
desvaloración: devaluation
desvalorización: devaluation
desvalorizar: to devalue, to depreciate
desvaluación: devaluation
desvanecer: to vanish; to fade
desvanecimiento: disappearance
desvariante: delusional
desvariar: to become delusional, to lose one's mind
desvarío: delirium
desvasar: to trim a horse hoof before shoeing it
desvaído: dull; dim; dull; boring; lacklustre
desvaír: to lose color, strength or intensity
desvelado: unable to sleep; sleepless (during which one cannot sleep)
desvelamiento: revealing; uncovering
desvelar: to prevent someone from sleeping; to keep awake; to be unable to sleep; to be vigilant; to work tirelessly
desvelar: to reveal, unveil
desvellado: bald, hairless
desvelo: insomnia; attention, care, interest
desvenado: deveined
desvenar: to devein
desvencijado: rickety; ramshackle
desvencijar: to break down
desventaja: disadvantage, drawback, downside, weakness
desventajado: disadvantaged
desventajar: to put at a disadvantage; to disfavour
desventajosamente: disadvantageously, unprofitably, unfavorably
desventajoso: disadvantageous, unprofitable, unfavorable
desventar: to let out air
desventrar: to rip the guts of; eviscerate; disembowel
desventura: misfortune; unhappiness; trouble
desventuradamente: unfortunately; lucklessly