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8,200 words — headwords with part of speech, pronunciation, and a plain-language definition.

espiramicina: spiramycin
espirantizar: to spirantize
espirar: to exhale
espiratorio: expiratory
espiritismo: Spiritism (a religious and philosophical doctrine concerned with communication with the dead)
espiritista: spiritualistic
espiritista: spiritualist
espiritoso: strongly alcoholic
espiritrompa: spiritrompe, haustellum
espiritual: spiritual (a Christian religious song)
espiritual: spiritual
espiritualidad: spirituality
espiritualismo: spiritualism
espiritualista: spiritualist
espiritualista: spiritualist
espiritualización: spiritualization
espiritualizar: to spiritualize
espiritualmente: spiritually
espirituano: native or inhabitant of Sancti Spíritus (city and municipality of Cuba) (usually male)
espirituano: of, from or relating to Sancti Spíritus (city and municipality of Cuba)
espirituar: possess
espirituoso: spirituous; strongly alcoholic
espirometría: spirometry
espirométrico: spirometric
espironolactona: spironolactone
espiropapa: potato sliced into a spiral shape
espiroqueta: spirochete (bacteria of the phylum Spirochaetes)
espirto: obsolete spelling of espíritu
espirtu: obsolete spelling of espíritu
espirulina: spirulina
espiráculo: blowhole, airhole, spiracle
espirómetro: spirometer (medical device that measures the volume of air inspired and expired by the lungs)
espita: spigot, tap; spile; boozehound; dick; prick (penis)
espitar: to put a spigot or tap
espitoso: high; buzzing; euphoric (said of a drug)
esplanar: to flatten
esplendente: shining; glowing
esplender: to shine, gleam
esplendidez: splendidness, magnificence
esplendor: splendour/splendor
esplendorosamente: splendidly
esplendoroso: magnificent, splendorous
esplenectomía: splenectomy
esplenio: splenius
esplenitis: splenitis
esplenomegalia: splenomegaly
esplenorrenal: splenorenal
esplicar: pronunciation spelling of explicar
espliceosoma: spliceosome
espliego: lavender
esplorador: obsolete spelling of explorador
esplácnico: splanchnic
espléndidamente: splendidly, magnificently
espléndido: splendid, magnificent, splendiferous, superb, lavish, glorious; gorgeous
esplénico: splenic; splenetic
esplín: spleen; melancholy
espodumena: spodumene
espolazo: prick from a spur (for horses)
espolear: to spur on; to goad; to spark
espoleta: wishbone (of a bird)