autoaislarse

To self-isolate — withdraw from social contact, whether for health reasons (quarantine) or emotionally: se autoaisló durante la cuarentena. The word saw a sharp spike in everyday use during the COVID-19 pandemic and has stuck around since.

• Se autoaisló en casa al notar los primeros síntomas. — He self-isolated at home when he noticed the first symptoms.
• Después de la ruptura, tendió a autoaislarse de sus amigos. — After the breakup, he tended to isolate himself from his friends.
• Las autoridades recomendaron autoaislarse ante cualquier síntoma. — The authorities recommended self-isolating at the first sign of symptoms.

Using autoaislarse only for the pandemic sense — it works just as naturally for voluntary emotional or social withdrawal, with no illness involved.